Prof. Dr. Frederik Börnke
Prof. Dr.
Frederik Börnke
Großbeeren
033701 - 78 219
boernke@igzev.de
Scientist
komm. Leiter Programmbereich 1
Ausbildung
Berufliche Tätigkeiten
Sonstige Tätigkeiten
| Head (acting) of Programme Area 1
Head of Research Group 1.2 Professor for Plant Metabolism Institute of Biology and Biochemistry Universität Potsdam |
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| Research profile | |
| Main research areas are the analysis of the regulatory properties of enzymes of primary plant metabolism, the control of gene expression through metabolic signals, and the regulation of cellular processes through protein-protein interactions. Beyond that, he is studying plant-bacteria interactions on the molecular level in order to understand how pathogens re-program host cellular processes for their own benefit. This also involves the analysis of plants as hosts for human enteropathogenic bacteria. | |
| Professional appointments | |
| Since 2013 | Professor of Plant Metabolism, Institute of Biology and Biochemistry, Universität Potsdam and Group Leader at the IGZ |
| 2013 | Professor of Crop Plant Biochemistry, Institute of Plant Nutrition, Justus Liebig Universität Gießen |
| 2004–2013 | Group Leader, Division of Biochemistry at the Friedrich-Alexander-Universität Erlangen-Nürnberg |
| 2002–2004 | Group Leader “Molecular Networks“, Leibniz Institute of Plant Genetics and Crop Plant Research,, Department Molecular Cell Biology |
| 2001–2002 | Post-Doc at the Leibniz Institute of Plant Genetics and Crop Plant Research, Department Molecular Cell Biology |
| Education | |
| 2008 | Habilitation and venia legendi in Biochemistry at the Faculty of Natural Sciences, Friedrich-Alexander-Universität Erlangen-Nürnberg |
| 1997–2001 | PhD at the Leibniz Institute of Plant Genetics and Crop Plant Research |
| 1990–1996 | Studies of Biology, Georg-August-Universität Göttinge |
| Major engagements and other professional roles (selection) | |
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| Teaching and supervision | |
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STOREKEEPER RELATED 1/G-element Binding Protein (STKR1) interacts with protein kinase SnRK1
Nietzsche, M.; Guerra, T., Alseekh, S.; Wiermer, M.; Sonnewald, S.; Fernie, A.R.; Börnke, F. 2018. STOREKEEPER RELATED 1/G-element Binding Protein (STKR1) interacts with protein kinase SnRK1. Plant Physiology.
DOI: 10.1104/pp.17.01461
→Thigmomorphogenesis – Control of plant growth by mechanical stimulation
Börnke, F.; Rocksch, T. 2018. Thigmomorphogenesis – Control of plant growth by mechanical stimulation. Scientia Horticulturae 234, 344-353.
DOI: 10.1016/j.scienta.2018.02.059
→A proteomic approach suggests unbalanced proteasome functioning induced by the growth-promoting bacterium Kosakonia radicincitans in Arabidopsis.
Witzel, K.; Üstün, S.; Schreiner, M.; Grosch, R.; Börnke, F.; Ruppel, S. 2017. A proteomic approach suggests unbalanced proteasome functioning induced by the growth-promoting bacterium Kosakonia radicincitans in Arabidopsis. Frontiers in Plant Science 2017 8:661.
→A Two-Faced Cochaperone Involved in Pattern Recognition Receptor Maturation and Viral Infection
Lamm, C.; Kraner, M.; Hofmann, J.; Börnke, F.; Mock, H.P.; Sonnewald U. 2017. Hop/Sti1 – A Two-Faced Cochaperone Involved in Pattern Recognition Receptor Maturation and Viral Infection. Front Plant Sci. 2017 Oct 11;8:1754.
DOI: 10.3389/fpls.2017.01754. eCollection 2017.
→Ubiquitin Proteasome Activity Measurement in Total Plant Extracts.
Üstün, S.; Börnke, F. 2017. Ubiquitin Proteasome Activity Measurement in Total Plant Extracts. Bio-protocol 7(17): e2532.
DOI: 10.21769/BioProtoc.2532.
→A protein-protein interaction network linking the energy-sensor kinase SnRK1 to multiple signaling pathways in Arabidopsis thaliana.
Nietzsche, M.; Landgraf, R.; Tohge, T.; Börnke, F. 2016. A protein-protein interaction network linking the energy-sensor kinase SnRK1 to multiple signaling pathways in Arabidopsis thaliana. Current Plant Biology, 5, 36-44.
doi: 10.1016/j.cpb.2015.10.004.
http://www.sciencedirect.com/science/article/pii/S2214662815000158
→Quantitative phosphoproteomics reveals the role of the AMPK plant ortholog SnRK1 as a metabolic master regulator under energy deprivation.
Nukarinen E.; Nägele T.; Pedrotti L.; Wurzinger B.; Mair A.; Landgraf R.; Börnke F.; Hanson J.; Teige M.; Baena-Gonzalez E.; Dröge-Laser W.; Weckwerth W. 2016. Quantitative phosphoproteomics reveals the role of the AMPK plant ortholog SnRK1 as a metabolic master regulator under energy deprivation. Scientific Reports 6: 31697.
doi:10.1038/srep31697
→The proteasome acts as a hub for plant immunity and is targeted by Pseudomonas type-III effectors.
Üstün, S.; Sheikh, A.; Gimenez-Ibanez, S.; Jones, A.; Ntoukakis, V.; Börnke, F. 2016. The proteasome acts as a hub for plant immunity and is targeted by Pseudomonas type-III effectors. Plant Physiology 2016, 172 (2).
http://www.plantphysiol.org/content/early/2016/09/09/pp.16.00808.abstract
doi:10.1104/pp.16.00808
→The Xanthomonas campestris type III effector XopJ proteolytically degrades proteasome subunit RPT6.
Üstün, S.; Börnke, F. 2015. The Xanthomonas campestris type III effector XopJ proteolytically degrades proteasome subunit RPT6. Plant Physiology 116, 107-119.
→The Xanthomonas effector XopJ triggers a conditional hypersensitive response upon treatment of N. benthamiana leaves with salicylic acid.
Üstün, S.; Bartetzko, V.; Börnke, F. 2015. The Xanthomonas effector XopJ triggers a conditional hypersensitive response upon treatment of N. benthamiana leaves with salicylic acid. Frontiers in Plant Science, DOI:10.3389/fpls.2015.00599.
http://journal.frontiersin.org/article/10.3389/fpls.2015.00599/abstract
HopZ4 from Pseudomonas syringae, a member of the HopZ type III effector family from the YopJ superfamily, inhibits the proteasome.
Üstün, S.; König, P.; Gutmann, D.S.; Börnke, F. 2014. HopZ4 from Pseudomonas syringae, a member of the HopZ type III effector family from the YopJ superfamily, inhibits the proteasome. Molecular Plant-Microbe Interactions 27 (7) 611-623.
→Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways.
Üstün, S.; Börnke, F. 2014. Interactions of Xanthomonas type-III effector proteins with the plant ubiquitin and ubiquitin-like pathways. Frontiers in Plant Science, doi: 10.3389/fpls.2014.00736.
http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00736/abstract
Loss of the two major leaf isoforms of sucrose-phosphate synthase in Arabidopsis thaliana limits sucrose synthesis and nocturnal starch degradation but does not alter carbon partitioning during photosynthesis.
Volkert, K.; Debast, S.; Voll, L.M.; Voll, H.; Schießl, I.; Hofmann, J.; Schneider, S.; Börnke, F. 2014. Loss of the two major leaf isoforms of sucrose-phosphate synthase in Arabidopsis thaliana limits sucrose synthesis and nocturnal starch degradation but does not alter carbon partitioning during photosynthesis. Journal of Experimental Botany 65 (18), 5217-5229.
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Redox-activity of thioredoxin z and fructokinase-like protein 1 is dispensable for autotrophic growth of Arabidopsis thaliana.
Wimmelbacher, M.; Börnke, F. 2014. Redox-activity of thioredoxin z and fructokinase-like protein 1 is dispensable for autotrophic growth of Arabidopsis thaliana. Journal of Experimental Botany 65 (9), 2405–2413.
→The complex becomes more complex: protein-protein interactions of SnRK1 with DUF581 family proteins provide a framework for cell- and stimulus type-specific SnRK1 signaling in plants.
Nietzsche, M.; Schießl, I.; Börnke, F. 2014. The complex becomes more complex: protein-protein interactions of SnRK1 with DUF581 family proteins provide a framework for cell- and stimulus type-specific SnRK1 signaling in plants. Frontiers in Plant Science, doi: 10.3389/fpls.2014.00054
http://journal.frontiersin.org/Journal/10.3389/fpls.2014.00054/abstract
The Xanthomonas campestris Type III effector XopJ targets the host cell proteasome to suppress salicylic-acid mediated plant defence.
Üstün, S.; Bartetzko, V.; Börnke, F. 2013. The Xanthomonas campestris Type III effector XopJ targets the host cell proteasome to suppress salicylic-acid mediated plant defence. PLoS Pathogens 9(6): e1003427.
SseF, a type III effector protein from the mammalian pathogen Salmonella enterica, requires resistance-gene-mediated signalling to activate cell death in the model plant Nicotiana benthamiana.
Üstün, S.; Müller, P.; Palmisano, R.; Hensel, M.; Börnke, F. 2012. SseF, a type III effector protein from the mammalian pathogen Salmonella enterica, requires resistance-gene-mediated signalling to activate cell death in the model plant Nicotiana benthamiana. New Phytologist 194, 1046-1060.
→Plastidial Thioredoxin z interacts with two fructokinase-like proteins in a thiol-dependent manner: evidence for an essential role in chloroplast development in Arabidopsis and Nicotiana benthamiana.
Arsova, B.; Hoja, U.; Wimmelbacher, M.; Greiner, E.; Üstün, S.; Melzer, M.; Petersen, K.; Lein, W.; Börnke, F. 2010. Plastidial Thioredoxin z interacts with two fructokinase-like proteins in a thiol-dependent manner: evidence for an essential role in chloroplast development in Arabidopsis and Nicotiana benthamiana. 22, 1498-1515.
→A remorin from Nicotiana benthamiana interacts with the Pseudomonas type-III effector protein HopZ1a and is phosphorylated by the immune-related kinase PBS1
Albers, P.; Üstün, S.; Witzel, K.; Kraner, M.; Börnke, F. 2018. A remorin from Nicotiana benthamiana interacts with the Pseudomonas type-III effector protein HopZ1a and is phosphorylated by the immune-related kinase PBS1. bioRxiv 409235.
DOI:
MARD1/DUF19 is a possible mediator of crosstalk between energy and defense signaling in Arabidopsis.
Landgraf, R.; Niietzsche, M.; Börnke, F. 2015. MARD1/DUF19 is a possible mediator of crosstalk between energy and defense signaling in Arabidopsis. International Symposium “Communication in Plants and their Responses to the Environment”, Halle (Saale), Program and Abstratcs, 88.
The Pseudomonas springiae type III effector HOPZ1A targets a remorin possibly implicated in defense signaling.
Albers, Ph.; Üstün, S.; Börnke, F. 2015. The Pseudomonas springiae type III effector HOPZ1A targets a remorin possibly implicated in defense signaling. International Symposium “Communication in Plants and their Responses to the Environment”, Halle (Saale), Program and Abstratcs, 72.
The plant proteasome is required for local and systemic defense responses and acts as a virulence target of bacterial type-III effector proteins.
Üstün, S.; Ntoutakis, V.; Börnke, F. 2015. The plant proteasome is required for local and systemic defense responses and acts as a virulence target of bacterial type-III effector proteins. Botanikertagung 2015, Weihenstephan, Conference Book, 85.
The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling?
Nietzsche, M.; Börnke, F. 2015. The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling? International Symposium “Communication in Plants and their Responses to the Environment”, Halle (Saale), Program and Abstratcs, 92.
The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling?
Nietzsche, M.; Korpys, A.; Börnke, F. 2015. The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling? The 26th International Conference on Arabidopsis Research, Paris, Program and Abstratcs, 57.
The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling?
Nietzsche, M.; Korpys, A.; Börnke, F. 2015. The putative transcription factor STKR1: A novel component of SNRK1 mediated signaling? Botanikertagung 2015, Weihenstephan, Conference Book, 122.
http://www.botanikertagung2015.de/
Wie Pflanzen krank werden.
Börnke, F. 2015. Wie Pflanzen krank werden. Jahresbericht 2013/2014 des Leibniz-Institutes für Gemüse- und Zierpflanzenbau Großbeeren/Erfurt, 39.