Großbeeren
033701 - 78 250 
hanschen@igzev.de 
The Leibniz Junior Research Group OPTIGLUP (Optimization of Glucosinolate Degradation Pathways for Increased Quality and Health Benefit of Brassica Products) is funded by the Leibniz-Gemeinschaft and aims to optimize the glucosinolate degradation in Brassica vegetables, such as broccoli and cabbage. These plant metabolites are precursors of cancer preventing isothiocyanates. However, in these vegetables often other compounds, such as epithionitriles are formed from glucosinolates during vegetable processing. Thus, the goal of the Leibniz Junior Research Group is to optimize the glucosinolate degradation – during pre-harvest as well as during post-harvest- to induce isothiocyanate formation and to decrease the epithionitriles. Additionally, it will be investigated how other secondary plant metabolites affect the thermal degradation of glucosinolates, which occurs during cooking. Together with collaboration partners we will investigate, if newly identified compounds have health preventive effects.
QUALITY.2 OPTIGLUP-Optimization of Glucosinolate Degradation Pathways
QUALITY.2 OPTIGLUP-Optimization of Glucosinolate Degradation Pathways Head of Research Group QUALITY.2: Dr. rer. nat. habil. Franziska S. Hanschen
The degradation pathways of glucosinolates determine the health promoting effects of these secondary plant metabolites. In this context we aim to channel the glucosinolate degradation in a way that the beneficial products are formed preferentially.
The former junior research group QUALITY.1.JR is now the research group QUALITY.2.
Cooperation Partners
Determination of Isothiocyanate-Protein Conjugates in a Vegetable-Enriched Bread
Krell, M.; Cvancar, L.; Poloczek, M.; Hanschen, F.S.; Rohn, S. Determination of Isothiocyanate-Protein Conjugates in a Vegetable-Enriched Bread. Foods 2021, 10, 1300.
→Allyl Isothiocyanate: A TAS2R38 Receptor-Dependent Immune Modulator at the Interface Between Personalized Medicine and Nutrition
CO2 treatment increases glucosinolate hydrolysis products in two Arabidopsis thaliana accessions
Wiesner-Reinhold, M.; Nickel, M.; Graefe, J.; Schreiner, M.; Hanschen, F.S. (2021). CO2 treatment increases glucosinolate hydrolysis products in two Arabidopsis thaliana accessions. Journal of Applied Botany and Food Quality 94, 16 – 25 (2021), DOI:10.5073/JABFQ.2021.094.003
→Seasonal Variation of Glucosinolate Hydrolysis Products in Commercial White and Red Cabbages (Brassica oleracea var. capitata)
Seasonal Variation of Glucosinolate Hydrolysis Products in Commercial White and Red Cabbages (Brassica oleracea var. capitata). N. S. Wermter, S. Rohn, F. Hanschen Foods 2020, 9(11), 1682
→Biofumigation for fighting replant disease- A review
Hanschen, F.S.; Winkelmann, T. (2020). Biofumigation for fighting replant disease- A review. Agronomy, 10, 425,
DOI: 10.3390/agronomy10030425
→Stability of glucosinolate hydrolysis products and the identification of novel compounds in foods
F. S. Hanschen, J. Böttger, L. Andernach, J. Fechner, M. Kaufmann, S. Rohn, M. Schreiner: Stability of glucosinolate hydrolysis products and the identification of novel compounds in foods. EuroFoodChem XX Conference, 17. – 19. June 2017, Porto (Portugal), Program & Book of Abstracts (ISBN 978-989-8124-26-5), 86
Effect of water stress on glucosinolate content and their breakdown in pak choi (Brassica rapa L. ssp. chinensis)
V. Púčiková, F. S. Hanschen: Effect of water stress on glucosinolate content and their breakdown in pak choi (Brassica rapa L. ssp. chinensis). EuroFoodChem XX Conference, 17. – 19. June 2017, Porto (Portugal), Program & Book of Abstracts (ISBN 978-989-8124-26-5), 162
Identifizierung von N-Acetyl-S-(3-cyano-2-(methylsulfanyl)propylcystein, ein Hauptmetabolit von 1-Cyano-2,3-epithiopropan, dem wichtigsten Glucosinolatabbauprodukt von Weißkohl
F. S. Hanschen, S. Baldermann, A. Bobrowski, M. Wiesner-Reinhold, S. Rohn, M. Schreiner: Identifizierung von N-Acetyl-S-(3-cyano-2-(methylsulfanyl)propylcystein, ein Hauptmetabolit von 1-Cyano-2,3-epithiopropan, dem wichtigsten Glucosinolatabbauprodukt von Weißkohl. 48. Deutscher Lebensmittelchemikertag, 16.-18. September 2019, Dresden (Germany),Tagungsband Kurzreferate (ISBN 978-3-947197-15-6), 84
Mechanisms of Selenium Enrichment and Measurement in Brassicaceous Vegetables, and Their Application to Human Health
Wiesner-Reinhold, M., Schreiner, M., Baldermann, S., Schwarz, D., Hanschen, F. S., Kipp, A. P., Rowan, D. D., Bentley-Hewitt, K. L., & McKenzie, M. J. Mechanisms of Selenium Enrichment and Measurement in Brassicaceous Vegetables, and Their Application to Human Health. In N. Bertin, M. Génard & M. Hertog (Eds.), Quality of horticultural crops: a recurrent/new challenge for plant scientists in a changing world, Lausanne: Frontiers Media, 2018, pp. 183-202
→Nutritional Quality of Plants for Food and Fodder
Wiesner, F. S. Hanschen, R. Maul, S. Neugart, M. Schreiner, S. Baldermann: Nutritional Quality of Plants for Food and Fodder. In Brian Thomas, Brian G. Murray and Denis J. Murphy (Editors in Chief), Encyclopedia of Applied Plant Sciences, Vol 1, Waltham, MA: Academic Press, 2017, pp. 285–291.
UV-B-induced changes in secondary plant metabolites.
Schreiner, M. Wiesner-Reinhold, S. Baldermann, F.S. Hanschen, S. Neugart: UV-B-induced changes in secondary plant metabolites. In B. Jordan (Ed.), UV-B Radiation and Plant Life). Oxfordshire, United Kingdom: CABI. 2017
→The Physiology of Vegetable Crops
Neugart, F. S. Hanschen, M. Schreiner. Glucosinolates in Brassica. In H. C. Wien & H. Stützel (Eds.), The physiology of vegetable crops.: CABI. 2020, pp. 389-398.
→Current Project
InnoWild
Establishment of a cultivation and utilization system of native and climate-adapted wild plants w...
Other Projects
Joint Lab PhaSe – Phytochemistry and biofunctionality of plant Secondary metabolites
Subject of our research at the Joint Lab PhaSe is research how secondary plant metabolites – e.g. carotenoids, glucosinolates, and polyphenol...
OPTIGLUP-Optimization of Glucosinolate Degradation Pathways for Increased Quality and Health Benefit of Brassica
The Junior-Research Group OPTIGLUP-Optimization of Glucosinolate Degradation Pathways for Increased Quality and Health Benefit of Brassica Products, financed...
ENATGLUPRO- Enzymatic and non-enzymatic degradative reactions during the thermal treatment of glucosinolates and their reaction products
Glucosinolates are secondary plant metabolites in crops of the Brassicaceae family (e.g. broccoli, cabbage) that may help preve...